mock test  Biochemisty

Biochemistry 24 Ques. / 20 min.



1) Formation of ammonium ions to remove the excess acid in urine is produced by which of the following enzymes:

One answer only.
   Glutaminase
   Glutamate pyruvate transaminase
   Glutamate dehydrogenase
   Carboxylase



2) Which of the following amino acids un-dergoes hydroxylation and is involved in the formation of collagen:

One answer only.
   Proline
   Tryptophan
   Phenylalanine
   cystiene



3) The long chain fatty acids are transmitted across the inner membrane of mitochondria by :

One answer only.
   Acyl carrier protein
   carnitine
   Glycoprotein
   None of the above



4) Restriction endonuclease is used in :

One answer only.
   Recombinant DNA technology
   For splicing DNA
   For genetic engineering
   None of the above



5) Chromosome 5 is associated with :

One answer only.
   Ulcerative colitis
   Familial adematosis polyposis
   Crohn's disease
   Down's syndrome



6) Heme synthesis true is :

One answer only.
   ALA synthesis is catalysed by thiamine pyrophosphate
   Ferochelatase is inhibited by lead
   variegate porphylia is due to deficiency of uroporphyrin synthase
   Protoporphyrin oxidase is a cytosolic coenzyme



7) In respiratory cycle regarding ATP formation by oxidative phosphorylation true is A/E :

One answer only.
   Inhibited by oligomycin
   Binds to molecular oxygen
   Takes place on the matrix side of mitochondria
   facilitated through protons



8) Polymerase chain reaction is used for :

One answer only.
   Amplification of human DNA
   Detecting RNA
   Detecting DNA
   To breack dsDNA to ssDNA



9) In metobolism of hydrogenperoxide by catalase and peroxidase, the latter requires which of the following ?

One answer only.
   GSH
   GSSG
   NADH
   NADPH



10) Which of the following is true about vit. K?

One answer only.
   Increases bleeding tendencies in the newborn
   Synthesized by intestinal bacteria
   It prevents thrombosis
   Increases coagulation time



11) The organism used for the first time and commonly used in recombinant DNA technology is :

One answer only.
   Proteus
   Pneumococcus
   E.coli
   Shigella



12) The Refsum's disease in which there is accumulation of phytanic acid is due to defect of :

One answer only.
   Alpha-oxidation
   Beta-oxidation
   HMG-CoA lyase deficiency
   Carnitine palmitoyl transferase I deficiency



13) Enzyme deficient in Gaucher's disease is ;

One answer only.
   Beta-galactosidase
   Beta-glucosidase
   Sphinomyelinase
   Ceramidase



14) Initiator codon is :

One answer only.
   AUG
   UGA
   UAA
   UAG



15) True about action of dinitrophenol is :

One answer only.
   Does not allow electron transport chain to continue, and no production of ATP
   Allows ETC to continue. No production of ATP
   Does not allow ETC to continue, but there is production of ATP
   Allows ETC to continue and production of ATP continues



16) The process in which amino group of the amino acid is transferred to the keto acid and the keto group of the keto acids transferred to the amino acid is called :

One answer only.
   Transamination
   Trans amidination
   Deamination
   Decarboxylation



17) Conversion of proline to hydroxyproline is by :

One answer only.
   Proline hydroxylase
   Reverse hydroxylation
   Post translation induction
   Vit. C mediated hydroxylation



18) In which of the following conditions anion gap is not found?

One answer only.
   Renal fubular acidosis
   Uraemic acidosis
   Respiratory acidosis
   Diabetic ketosis



19) In Nieman Picks disease enzyme deficient is :

One answer only.
   Beta-galactosidase
   Beta-glucosidase
   Sphingomyclinase
   Cerebrosidase



20) Which of the following is not a heme protein?

One answer only.
   Cytochrome oxidase
   Peroxidase
   Catalase
   NADH reductase



21) In which type of hyperlipidaemia cholesterol is increased but triglyceride is normal?

One answer only.
   Familial combined(mixed)hyperlipidemia
   Familial hyperchylomicronemia
   Familial hypercholesterolemia
   All of the above



22) HMG CoA reductase is the rate limiting enzyme in synthesis of :

One answer only.
   Low molecular weight triglycerides
   cholesterol
   High molecular weight triglycerides
   Chylomicrons



23) Fe" in hemoglobin molecule is stabilized by :

One answer only.
   Polar bond
   Nonpolar bond
   Lonic bond
   Coordination linkages



24) Which one of the enzyme deficiency is correctly paired?

One answer only.
   Farbers-Alpha galactosidase
   Gauchers-Beta glucosidase
   Nieman pick-Beta galactosidase
   Fabrys disease- Sphingomyelinase


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