ALL
INDIA 6th January 2002 MD/MS Entrance examination questions with suggested answers
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1 . In a case of hypertrophic pyloric stenosis, the metabolic disturbance is
- Respiratory alkalosis
- Metabolic acidosis
- Metabolic alkalosis with paradoxical
aciduria
- Metabolic alkalosis with alkaline
urine
Ans 3
2 .Sentinel lymph node biopsy is an important part of the management of which
of the following conditions?
1. Carcinoma prostate
2. Carcinoma breast
3. Carcinoma lung
4. Carcinoma nasopharynx
- In hyperthyroidism during pregnancy, which of the following is absolutely
contra-indicated?
- Surgery
- Radioiodine (I 131)
- Antithyroid drugs
- Iodine
Ans
2
- The most premalignant lesion
among the following is
- Leukoplakia
- Erythroplakia
- Metaplasia
- Dysplasia
Ans 2
- A previously healthy
45 year old construction worker develops acute low back pain, right leg pain,
and weakness of dorsiflexion of the great toe. True statements regarding this
case include which of the following?
- Immediate treatment should
include analgesics, muscle relaxants, and back strengthening exercises.
- The appearance of foot
drop would be an early indication for early surgery.
- Lumbar laminectomy and
excision of any herniated nucleus pulposus should be performed if the
presenting symptoms should fail to resolve in 1 week
- If the neurological signs
but not the back pain resolve in 2 to 3 weeks, proper treatment would
include fusion of affected lumbar vertebrae.
Ans 2
- A 26 year woman presents with
a palpable thyroid nodule, and needle biopsy demonstrates amyloid in the stroma
of the lesion. A cervical lymph node is palpable on the same side as the lesion.
The preferred treatment should be
- Removal of the involved
node, the isthmus, and the enlarged lymph node
- removal of the involved
lobe, the isthmus, a portion of the opposite lobe, and the enlarged lymph
node
- Total thyroidectomy and
modified neck dissection on the side of the enlarged lymph node
- Total thyroidectomy and
irradiation of the cervical lymph nodes
Ans 3
- A 75 year old woman underwent
neck exploration for hyperthyroidism 5 years ago, and a parathyroid adenoma
was excised. At the present time, she is recovering from a myocardial infarction
6 weeks ago, and she is in mild congestive heart failure. Her electrocardiogram
shows a slow atrial fibrillation. Measurement of her serum calcium shows a
level of 13.0 mg/dl and urine calcium is 300 mg/24h. Studies suggest a small
mass in the paratracheal position behind the right clavicle. Appropriate management
at this time is
- Observation and repeat
calcium levels in two months
- Repeat neck exploration
- Treatment with technetium-99
- Ultrasound guided alcohol
injection of the mass
Ans 4
- A 24 year old man falls to
the ground when he is struck in the right temple by a base ball. While being
driven to the hospital he lapses into coma. He is unresponsive with a dilated
right pupil when he reaches the emergency department. The most appropriate
step in initial management is
- CT scan of the head
- Craniotomy
- Doppler ultrasound examination
of the neck
- X rays of the skull and
cervical spine
Ans 2
- All the following are correct
about radiologic evaluation of a patient with Cushing’s syndrome except
- Adrenal CT scan distinguishes
adrenal cortical hyperplasia from an adrenal tumor
- CT of sella tursica is
diagnostic when a pituitary tumor is present
- MRI of the adrenals may
distinguish adrenal adenoma from carcinoma
- Petrosal sinus sampling
is the best way to distinguish tumor from an ectopic ACTH producing tumor
Ans 2
- Ten days after a splenectomy
for abdominal trauma, a 23 year old man complains of upper abdominal and lower
chest pain exacerbated by deep breathing. He is anorectic but ambulatory and
otherwise making satisfactory progress. On physical examination, his treatment
is 38.2 C rectally, and he has decreased breath sounds at the left lung base.
His abdominal wound appears to be healing well, bowel sounds are active, and
there are no peritoneal signs. Rectal examination is negative. The white blood
cell count is 12,500/mm3 with a shift to the left. Chest x-rays
show plate like atelectasis of the left lung field. Abdominal x-rays show
a nonspecific gas pattern in the bowel and an air fluid level in the left
upper quadrant. Serum amylase is 150 Somogyi units per dl.The most likely
diagnosis
- Subphrenic abscess
- Subfascial wound infection
- Pancreatitis
- Pulmonary embolism
Ans 1
- A 59 year old woman had a
left femoral venous thrombosis during a pregnancy 30 yrs ago. The left greater
saphenous vein had been stripped at age 21.She now presents with a large non
healing ulceration over medial calf, which has progressed despite bedrest,
elevation and use of a support stocking. Descending phlebography of
the left leg demonstrates a patent deep venous system. With free flow of dye
from the groin to foot. The first profunda femoris valve is competent. Appropriate
management might include which of the following?
- Division of the superficial
femoral vein in the groin and transplantation of its distal end below
the level of the competent profunda valve
- Saphenous venous crossover
graft with anastomosis of the end of the right saphenous vein onto the
side of the left common femoral vein
- Left iliofemoral venous
thrombectomy with creation of a temporary arteriovenous fistula
- Subfascial ligation of
perforating veins in the left calf
Ans 1
- A 16 year old girl who has
nonpitting edema of recent onset affecting her right leg but no other symptoms
is referred for evaluation. True statements about this patient include all
the following except
- A lymphangiogram probably
will show hypoplasia of the lymphatics
- Prophylactic antibiotics
are indicated
- Elastic support and diuretics
will restore the affected limb to normal appearance
- A variety of operations
will restore the affected limb to a normal appearance
Ans
4
- A 14 year old girl sustains
a steam burn measuring 6 by 7 inches over the ulnar aspect of her right forearm.
Blisters develop over the entire area of the burn wound, and by the time the
patient is seen 6 hour after the injury, some of the blisters have ruptured
spontaneously. In addition to debridement of the necrotic epithelium, all
the following therapeutic regimens might be considered appropriate for this
patient except
- Application of silver
sulfadiazine and daily washes, but no dressing
- Application of Polyvinylpyrrolidone
foam, daily washes and a light occlusive dressing changed daily
- Application of mafenide
acetate cream, but no daily washes or dressing
- Heterograft application
with sutures to secure in place and daily washes, but no washes
Ans 4
- A man 70 kgs is transferred
to a burn centre 4 weeks after sustaining a 2nd and 3rd
degree burn injury to 45% of his total body surface area. Prior to accident
the patient’s weight was 90 kgs. The patient has not been given anything by
mouth since the injury, except for antacids because of a previous ulcer history.
On examination the patients burn wound are clean, but only minimal healing
is evident and thick adherent eschar present. The patient’s abdomen is soft
and non distended and active bowel sounds are heard. His stools are trace
positive for ` and he has a reducible right inguinal hernia, which appears
to be easily reducible. He has poor range of motion of all involved joints
and has developed early axillary and popliteal fossae flexion contractures.
In managing this patient at this stage of his injury, top priority must be
given to correcting
- The open, poorly healing
burn wounds by surgical excision and grafting
- The inguinal hernia by
surgical repair using local anesthetic
- The nutritional status
by enteral supplementation or parenteral hyperalimentation
- By increasing the dose
of antacids and adding cimetidine
Ans 3
- On her third of hospitalization,
a 70 year old woman who is being treated for acute cholecystitis develops
increased pain and tenderness in the right upper quadrant with a palpable
mass. Her temperature rises to 104 F and her BP falls to 80/60.Heametamesis
and malena ensue and petechiae are noted. Laboratory studies reveal thrombocytopenia,
prolonged PT, and decreased fibrinogen level. The most important step in the
correction of this patients coagulopathy
1.
Administration of heparin
2.
administration of fresh frozen plasma
3.
Administration of Epsilon amino caproic acid
4.
Exploratory laparotomy
Ans
4
- A 64 year old previously healthy
man is admitted to a hospital because of a closed head injury and ruptured
spleen following an automobile accident. During the first 4 days of hospitalization,
following laparotomy and splenectomy, he receives 5% dextrose ½ normal saline
solution at a rate of 125 mL/hr. Recorded daily fluid outputs include 450-600
mL of nasogastric tube drainage and 700-1000 mL of urine. The patient is somnolent,
but easily aroused until the morning of the 5th hospital day, when
he is noted to be in deep coma, by the afternoon he begins having seizures.
The following laboratory data are obtained.
Serum
electrolytes: Na 130, K 1.9, Cl 96 and HCO3 19
Serum
osmolality 260 mosm/L
Urine
electrolytes: Na 61, K 18.
Which of the following statements about diagnosis or treatment of this patient’s
condition is true?
1.
His Hypokalemia is probably secondary to metabolic acidosis
2.
An emergency carotid arteriogram should be obtained as the first step
in his management
3.
An i.v infusion of 20 ml of 50% Magnesium Sulphate should be given
over a 4 hour paired as the first step in his management
4.
A small quantity of hypertonic saline solution should be given as the
first of his management
Ans 4
- An ultrasound in a 3 year
old child shows a 3 cm circumscribed hypoechoic mass in the abdomen. The diagnosis
is most likely to be
- Neuroblastoma
- Wilm’s tumor
- Oncocytoma
- Renal cell carcinoma
Ans
2
- A 6 month old child was found
to have grade IV vesicoureteric reflux. The bladder wall is normal. The treatment
of choice would be
- Ureteric reimplantation
- Teflon injection to ureteric
orifices
- Antibiotics and observe
- Endoscopic ureteric resection
Ans
1
- All are seen in thromboangiitis
obliterans except
- Intermittent claudication
- Migratory superficial
thrombophlebitis
- Raynaud’s phenomenon
- Absent popliteal pulsation
Ans
4
- A patient with external hemorrhoids
develops pain while passing stools. The nerve mediating this pain is
- Hypogastric nerve
- Pudendal nerve
- Splanchnic visceral nerve
- Sympathetic plexus
Ans
2
- A patient operated for carcinoma
colon 4 months back now presents with a 2 cm solitary mass in the liver. The
best line of management is
- Radiotherapy
- Radiofrequency ablation
- Resection
- CT scan
Ans
3
- The triad as originally described
by Zollinger and Ellison is
- Hypergastrinemia, raised
gastric acid output, beta cell tumor
- Hypergastrinemia, raised
gastric acid output, non beta cell tumor
- Hyochlorhydria, raised
gastric acid output, beta cell tumor
- Tumor of papilla of Vater,
hypergastrinemia, raised gastric acid output
Ans
2
- The most appropriate route
for the administration of significant proteins and calories to a patient comatose
for a long period after an automobile accident is by
- Nasogastric tube feedings
- Gastrostomy tube feedings
- Jejunostomy tube feedings
- Total parenteral nutrition
Ans
3
- A patient is admitted to the
hospital with burns. The young intern doing the saphenous cut down noted that
the patient developed pain and paresthesia along the dorsomedial aspect of
the leg following the procedure. The nerve most likely to have been involved
is
- Saphenous nerve
- Sural nerve
- Superficial peroneal nerve
- Deep peroneal Nerve
Ans
1
- An edentulous patient has
carcinoma of the oral cavity infiltrating into the alveolar margin. Which
of the following would not be indicated in managing the case?
- Segmental mandibulectomy
- Marginal mandibulectomy
with removal of the outer table
- Marginal mandibulectomy
with removal of upper half of mandible
- Radiotherapy
Ans
2
- A 9 month old infant presented
with features of intestinal obstruction. On barium enema, the diagnosis was
confirmed to be intussusception. The most likely etiology would be
- Meckel’s diverticulum
- Hypertrophic Peyer’s patch
- Mucosal polyp
- Lipoma
Ans
2
- A newborn presenting with
intestinal obstruction showed on abdominal Xray multiple air fluid levels.
The diagnosis is not likely to be
- Pyloric obstruction
- Duodenal atresia
- Ileal atresia
- Ladd’s bands
Ans
3
- In gastric outlet obstruction
in a duodenal ulcer patient, the site of obstruction is most likely to be
- Antrum
- Duodenum
- Pylorus
- Pyloric canal
Ans
1
- The treatment modality of
achalasia which has the maximum probability of causing a recurrence is
- Pneumatic dilatation
- Laparoscopic myotomy
- Botulinum toxin
- Open surgical myotomy
Ans
3
- True adenocarcinoma of esophagus
is most likely to be due to
- Achalasia
- Barret’s esophagus
- Patterson Brown syndrome
- Scleroderma
Ans
2
- Epithelium of Barret’s
mucosa is
- Ciliated columnar
- Columnar
- Stratified squamous
- Squamous
Ans
2
- The least recurrence of gastric
hypersecretion following surgery for peptic ulcer is seen with
- Vagotomy with gastrojejunostomy
- Antrectomy with vagotomy
- Highly selective vagotomy
- Truncal vagotomy
Ans
2
- All the following indicates
early gastric cancer except
- Involvement of mucosa
- Involvement of mucosa
and submucosa
- Involvement of mucosa,
submucosa and muscularis
- Involvement of mucosa,
submucosa and adjacent lymph nodes
Ans
3
- Gastric malignancy is predisposed
with
- Duodenal ulcer
- Gastric hyperplasia
- Intestinal metaplasia
III
- Blood group O
Ans
3
- Thyroid storm is seen in all
except
- Thyrotoxicosis
- Surgery for thyroiditis
- Surgery on thyroid
- I 131 therapy in thyrotoxicosis
Ans 4
- In a young patient with Aplastic
anemia, the treatment of choice is
- ATG
- Bone marrow transplantation
- Danazol
- G-CSF
Ans 2
- 37 .Investigation of choice for invasive amebiasis is
- Indirect hemagglutination
- ELISA
- Counter immune electrophoresis
- Microscopy
Ans
2
38 .Stimulation with TSH is useful
for the diagnosis of
1. Prolactin
2. ACTH
3. Growth hormone
4. PTH
Ans
4
39 .In which of the following
conditions does hyperglycemia occur
- Addison’s disease
- Uremia
- Acromegaly
- Fever
Ans
3
40. Hypergastrinemia with hypochlorhydria
is seen in
- Zollinger Ellison Syndrome
- VIPoma
- Pernicious anemia
- Glucagonoma
Ans
3
41. Increased anion gap in urine
signifies
- Increased ammonium
- Increased H+
- Increased K+
- Increased Mg2+
Ans
1
42 .Raised anion gap in blood is
seen in all the following except
- Diabetic ketoacidosis
- Renal failure
- Chronic respiratory failure
- Antifreeze ingestion
Ans
3
43 .In Conn’s syndrome, all the
following are seen except
- Hypokalemia
- Hypernatremia
- Hypertension
- Edema
Ans
4
44 .In pheochromocytoma all the
following are seen except
- Episodic hypertension
- Orthostatic hypotension
- Wheezing
- Headache
Ans
3
45 .A 35 year old lady, Kamli, presenting
with severe headache was found to have a thyroid nodule with ipsilateral enlarged
cervical lymph nodes. She gave a history of her mother dying of thyroid cancer.
Which of the following investigations should be done prior to surgery?
- Urinary metanephrine
- Hydroxy indole acetic acid
in urine
- Urinary metanephrine and
VMA
- T3, T4 and
TSH
Ans
3
46 .A diabetic patient with blood
glucose of 600 mg/dL, Na 122 mEq/L was treated with insulin. After giving insulin
the blood glucose decreased to 100 mg/dL. What changes in blood Na level is
expected?
- Increase in Na level
- Decrease in Na level
- No change would be expected
- Na would return to previous
level spontaneously on correction of blood glucose
Ans
4
47 .A young lady with spontaneous
abortions has a history of joint pains and fever. She currently presents with
thrombosis of her leg vein. Her APTT is prolonged. The diagnosis is most likely
to be
- Inherited protein C and
S deficit
- Factor XII deficiency
- Antiphospholipid antibody
syndrome
- Increased antithrombin III
levels
Ans
3
48 .In antiphospholipid antibody
syndrome all the following are seen except
- Recurrent fetal loss
- Neurological symptoms
- Thrombocytosis
- Prolonged APTT
Ans
3
49 .Prophylactic spinal irradiation
is given in all except
- Acute lymphatic leukemia
- Non Hodgkin’s lymphoma
- Hodgkin’s lymphoma
- Small cell carcinoma of
lung
Ans
3
50. Craniospinal irradiation is
useful in which of the following conditions?
- Pilocytic astrocytoma
- Oligodendroglioma
- Medulloblastoma
- Oncocytoma
Ans
3
51 .Medullary cystic disease of
the kidney is best diagnosed by
- Ultrasound
- Nuclear scan
- Urography
- Biopsy
Ans
4
52 .A patient presents with hypertension
and dizziness. The X-ray shows anterior rib notching. The diagnosis is most
likely to be
- Pheochromocytoma
- Coarctation of the aorta
- Neurofibromatosis
- Marfan syndrome
Ans
2
53 .All the following are true regarding
Ramsay Hunt syndrome except
- It has a viral etiology
- VII nerve is involved
- VIII nerve may be involved
- Excellent prognosis if spontaneous
recovery occurs
Ans
4
54 .Renal vein thrombosis is most
likely in which of the following conditions?
- Membranous Glomerulonephritis
- Membranoproliferative Glomerulonephritis
- Rapidly progressive Glomerulonephritis
- Minimal Change disease
Ans 1
55 .Renal osteodystrophy differs
from nutritional and metabolic rickets due to the presence of
- Hyperphosphatemia
- Hypercalcemia
- Hypophosphatemia
- Hypocalcemia
Ans
1
56 .A patient has presented to you
with pleural effusion. The best site of aspiration of the fluid would be through
the
- 5th intercostal
space in the midclavicular line
- 2nd intercostal
space close to the sternum
- 7th intercostal
space in mid axillary line
- 10th intercostal
space in paravertebral location
Ans
3
57 .A 10 year old child presents
with anemia and recurrent fractures. The Xray shows diffuse hyperdensity of
bone. The diagnosis is most likely to be
- Osteogenesis imperfecta
- Osteopetrosis
- Osteochondroma
- Hyperparathyroidism
Ans
2
58 .In the JVP, all the following
combinations are true except
- c wave à
atrial systole
- ax descent à
atrial relaxation
- cy descent à
ventricular relaxation
- ya descent à
atrial filling
Ans
1
59 .All the following are correct
statements regarding findings in JVP except
- Cannon wave à
Complete heart block
- Slow vy descent à
Tricuspid regurgitation
- Giant cv wave à
Tricuspid stenosis
- Increased JVP with prominent
pulsations à SVC obstruction
Ans
1
60 .While inserting a central venous
catheter, a patient develops respiratory distress. The most likely cause is
- Hemothorax
- Pneumothorax
- Pleural effusion
- Hypovolumia
Ans 2
61 .The system internationale (SI)
unit for blood pressure is
- Torr
- mm Hg
- K Pa
- cm H2O
Ans
3
62 .Which of the following is not
seen in atrial myxoma?
- Fever
- Increased ESR
- Hypertension
- Embolic phenomenon
Ans
3
63 .A patient with nephrotic syndrome
with longstanding corticosteroid therapy may develop all the following except
- Hyperglycemia
- Hypertrophy of muscle
- Neuropsychiatric symptoms
- Suppression of the pituitary
adrenal axis
Ans
2
64 .All the following statements
about acute adrenal insufficiency are true except
- Acute adrenal insufficiency
is usually secondary to exogenous glucocorticoid administration
- Hyperglycemia is usually
present
- Hyperkalemia may present
as an acute cardiac problem
- Hyponatremia occurs as a
result of renal tubule sodium reabsorption (****)
Ans
2
65 .A patient who came for blood
donation was screened and found to be positive for HBsAg and HBeAg. His liver
transaminases were normal. The most important next step is
- Liver biopsy
- HBV DNA estimation
- Interferon therapy
- Observation and follow up
Ans 3
a i p g
66 .Antiretroviral prophylaxis decrease
the chances of transmission of HIV to fetus during pregnancy by
- 35%
- 50%
- 65%
- 75%
Ans
3
67 .All are true about De Quervain’s
thyroiditis except
- Raised ESR
- Subsides spontaneously
- Autoimmune etiology
- Pain and swelling of the
thyroid occurs
Ans
3
68 .Rheumatoid factor in rheumatoid
arthritis is important because
- RA factor is associated
with bad prognosis
- Absent RA factor rules out
the diagnosis of Rheumatoid arthritis
- It is very common in childhood
Rheumatoid arthritis
- It correlates with disease
activity
Ans
1
69 .Which of the following is seen
in ITP?
- Thrombocytosis
- Increased Prothrombin time
- Increased Bleeding time
- Increased clotting time
Ans
3
70 .A female 35 year old patient,
Radha, having children aged 5 and 6 years has history of amenorrhea and galactorrhea.
Blood examination reveals increased prolactin. The CT of head is likely to reveal
- Pituitary adenoma
- Craniopharyngioma
- Sheehan syndrome
- Pinealoma
Ans
1
71 .Glucose mediated release of
insulin is mediated through
- ATP dependent K channels
- cAMP
- Carrier modulation
- Receptor phosphorylation
Ans
1
72 .All the following are found
in brain dead patients except
- Decreased DTR
- Absent pupillary reflexes
- Complete apnea
- Heart rate not responding
to atropine
Ans 1
73 .A fracture of the lateral condyle
of femur underwent malunion with angulation. Which of the following deformity
is likely to occur
- Genu varum
- Genu valgum
- Genu recurvatum
- Tibia vara
Ans
2
74 .Patellar tendon bearing POP
cast is to be applied in
- Femoral fracture
- Patellar fracture
- Tibial fracture
- Medial malleolar fracture
Ans
3
75 .Inversion injury of foot is
associated with damage to all the following except
- Lateral malleolus
- Base of 5th metatarsal
bone
- Sustentaculum tali
- Extensor digitorum brevis
Ans
4
76 .True suproacondylar fracture
is associated with all except
- Extensor variety is more
common
- Uncommon in > 15 years
of age
- Varus is the most common
deformity
- Ulnar nerve is most commonly
involved
Ans
4
77 .The nerve most commonly involved
in Carpal tunnel syndrome is
- Median
- Ulnar
- Radial
- Musculocutaneous
Ans
1
78 .Fracture of surgical neck of
humerus causes damage to
- Axillary nerve
- Radial nerve
- Musculocutaneous nerve
- Ulnar nerve
Ans
1
79 .The position commonly seen in
posterior dislocation of hip is
- Internal rotation, flexion
and adduction
- Internal rotation, extension
and adduction
- External rotation, flexion
and adduction
- External rotation, extension
and adduction
Ans
1
80 .A 60 year old patient, Ramesh,
has on Xray, an expansile solitary tumor in the center of the metaphysis with
endosteal scalloping and with presence of punctuate calcification. The likely
diagnosis is
- Simple bone cyst
- Chondrosarcoma
- Osteochondroma
- Osteosarcoma
Ans
2
81 .A patient had an accident and
sustained fracture of his femur. 48 hours later, he developed tachypnea, disorientation
and conjunctival petechiae. The diagnosis is most likely to be
- Hypovolumia
- Air embolism
- Fat embolism
- Hyponatremia
Ans
3
82 .A child is brought with severe
scoliosis. On examination, there is partial fusion of lumbar vertebrae with
overlying tuft of hair along with neurological deficit. The diagnosis is most
likely to be
- Caudal regression syndrome
- Tight spinal band
- Diasteatomyelia
- Coccygeal cyst
Ans 3
83 .The gas which produces systemic
toxicity without causing local irritation is
- Ammonium
- Carbon monoxide
- Hydrocyanic acid
- Sulfur dioxide
Ans
2
84 .In a patient with fixed respiratory
obstruction Helium is used along with Oxygen instead of plain oxygen
because
- It increases the absorption
of oxygen
- It decreases the turbulence
- It decreases the dead space
- For analgesia
Ans 2
85 .Upper respiratory tract infection
is a common problem in children. All the following anesthetic complications
can occur in children with respiratory infections except
- Bacteremia
- Halothane granuloma
- Increased mucosal bleeding
- Laryngospasm
Ans 2
86 .A 2 year old child weighing
6.7 kg and with a history of diarrhea and vomiting for 2 days is brought to
the hospital. On examination, the skin when pinched up took almost seconds to
return to normal. Which of the following is the most likely diagnosis?
- No dehydration
- Some dehydration
- Severe dehydration
- Skin pinching is not reliable
in making a diagnosis
Ans
1
87 .A child was brought 6 hours
after a snake bite. On examination a localized edema of less than two inches
edema was present at the site of the bite. There were no systemic signs and
symptoms. The most correct management would be
- Incision and suction
- Inject antivenom locally
- Polyvalent antivenom should
be started i.v
- Observe for progression
of symptoms
Ans
4
88 .In a newborn with respiratory
distress syndrome, all the following are true except
- Increased incidence in <
34 weeks
- More common in infants of
diabetic mothers
- 100% oxygen is given in
treatment
- Cyanosis is present
Ans
3
a i p p
g
89 .A newborn was brought with persistent
crying and was found to have rashes. On laboratory examination, it was found
to have lactic acidosis. The diagnosis is likely to be
- Organic aciduria
- Urea cycle defect
- MELAS with lactic acidosis
- Aminoacidopathy
Ans
1
90 .A 12 week old child should be
further evaluated for developmental delay if found to have which of the following
defects?
- Failure to raise head to
90 degrees
- Fails to vocalize
- Unable to make babbling
noises
- Does not transfer a red
ring even when given in hand
Ans 1
91 .A 6 month old infant develops
high grade fever which subsided after 3 days following which there was appearance
of a generalized rash which too subsided after 48 hours without any residual
pigmentation. Which of the following is the most likely diagnosis?
- Fifth disease
- Roseola infantum
- Measles
- Rubella
Ans
2
92 .All the following are seen in
congenital rubella syndrome except
- Mental retardation
- Aortic stenosis
- Dearness
- Patent ductus arteriosus
Ans
2
93 .All are important causes of
post neonatal mortality in India except
- Respiratory infections
- Diarrhea
- Malnutrition
- Tetanus
Ans 4
94 .An eleven month child was found
to be very restless and hyperactive in the classroom making it difficult for
the other students in the classroom to concentrate. He
runs round the class all the day cannot sit at one place for a long time. He
gets very agitated when the toy in his hand is taken away. The most probable
diagnosis is
- Autism
- Conduct disorder
- Attention deficit hyperactivity
disorder
- Conversion
Ans 3
95 .All are true regarding hallucinations
except
- It represents a state of
inner mind’s spatial orientation
- It is independent of the
observer
- It is under voluntary control
- It is the perception which
occurs in the absence of stimulus
Ans
3
96 .A patient presents has a history
of continuous headache for the past 8yrs. Repeated examinations had failed to
reveal any lesion. The patient is not convinced and is convinced that he has
a tumor in his brain. He is referred to a psychiatrist, who, after examination
of his case comes to a conclusion. The diagnosis is most probably
- Hypochondriasis
- Somatization
- Somatoform pain disorder
- Obsessive Compulsive Disorder
Ans
1
97 .Which of the following behavioral
problems would suggest an organic brain lesion?
- Formal thought disorder
- Auditory hallucinations
- Visual hallucinations
- Depression
Ans
3
98 .Delusions are seen in
all the following except
- Obsessive compulsive disorder
- Depression
- Mania
- Schizophrenia
Ans
1
99 .A known alcoholic stops taking
alcohol for 2 days. After which he develops insomnia, altered sensorium, restlessness.
The diagnosis is most likely to be
- Delirium tremens
- Korsakoff’s psychosis
- Conversion
- Schizophrenia
Ans 1
100 .A patient was brought with a
history of behavioral problems. He has episodes of flailing of the arms and
legs and he has no memory of these episodes. The diagnosis is most likely to
be
- Acute panic disorder
- Temporal lobe seizures
- Generalized anxiety
- Hysteria and conversion
disorders
Ans 2
101 .A young lady presents with a
history of excessive food intake following which she would induce vomiting.
The diagnosis is most likely to be
- Binge eating disorder
- Bulimia nervosa
- Anorexia Nervosa
- OCD
Ans 2
102 .Regarding cholestasis of pregnancy,
all the following statements are true except
- Bilirubin more than 5 mg/dL
- SGPT/SGOT ratio less than
60 units
- Presence of severe itching
- Alkaline phosphatase is
increased maximally
Ans
1
103 .A young male patient presenting
with infertility underwent semen analysis. His sperm count was 15000 with motility
60% and no clot formation and his sperm count being 30000 with 40% normal cells.
The interpretation of this would be
- Oligospermia
- Azoospermia
- Motility disorder
- Antisperm antibodies
Ans 1
104 .All are true about cephalhematoma
except
- Occurs due to subcutaneous
edema
- Seen mostly over occipital
bone
- Treatment is by aspiration
- Varies in size when the
child cries
Ans
4
105 .All are true regarding episiotomy
except
- Increases the size of the
birth canal
- Midline episiotomy causes
less bleeding and heals early
- Involvement of rectum is
classified as grade 3/ 4
- Higher infection rate in
mediolateral episiotomy
Ans 2/4
106 .All are indications for cesarean
section except
- Placenta previa grade 4
- Abruptio placenta
- Carcinoma cervix Stage IB
- Active herpetic lesion
Ans 2
107 .A patient, Shalu, presents with
vaginal discharge. Examination of the discharge reveals the presence of Chlamydial
infection. The treatment of choice is
- Azithromycin + contact tracing
- Doxycycline + Metronidazole
- Fluconazole + Doxycycline
- Metronidazole
Ans 1
108 .Which of the following is seen
in infant of a diabetic mother?
- Hypercalcemia
- Hyperflycemia
- Increased blood viscosity
- Hyperkalemia
Ans 3
109 .A 45 year old female presents
with polymenorrhea of 6 months duration. Which of the following is the next
best line of management?
- Dialtation and curettage
- Oral contraceptives for
3 cycles
- Progesterone for 3 cycles
- Hysterectomy
Ans 4
110 .A patient presents with menorrhagia.
All the following are possible treatment modalities except
- NSAIDs
- Tranexamic acid
- Progesterone
- Clomiphene
Ans 4
111 .In a patient suspected to have
polycystic ovarian disease, LH and FSH should be examined in which part of the
menstrual cycle?
- 1-3 days
- 8-10 days
- 13-16 days
- 24-28 days
Ans 3
112 .Endometrial carcinoma is predisposed
to by all the following except
- Ethinyl estradiol
- Tamoxifen
- Oral contraceptives
- Nulliparity
Ans 3
113 .Complete failure of fusion of
the mullerian duct leads to
- Uterus didelphys
- Arcuate uterus
- Subseptate uterus
- Unicornuate uterus
Ans 1
114 .A patient with infertility and
PID was investigated and was found in hysterosalpingogram to have beaded fallopian
tubes with clubbing of the ampullary end. The diagnosis is most likely to be
- Gonococcus
- Chlamydia
- Tuberculosis
- Ureaplasma
Ans 3
115 .All the following are causes
of breech presentation except
- Cornual implantation
- Uterine malformation
- Fetal malformation
- Placenta accreta
Ans 4
116 .Which is true regarding instrumental
deliveries
- The only pre-requisite is
full cervical dilatation
- If venthouse fails, forceps
may be used
- Forceps can be used in breech
deliveries
- Venthouse cannot be used
in rotational deliveries (posterior and transverse presentations)
Ans 3
117 .A 25 year old female, Kamla,
with mitral stenosis having Class II symptoms, underwent pregnancy. All the
following are done for managing this patient except
- Application of outlet forceps
to cut short the 2nd stage
- After delivery of the placenta,
intravenous frusemide to be given
- Methergine is to be administered
after delivery of the anterior shoulder
- Antibiotic is to be given
Ans 3
118 .Which of the following changes
occurs in the vagina during pregnancy?
- pH increases
- Increase in lactobacilli
- Increase in anaerobic bacteria
- Decrease in glycogen content
Ans 4
119 .A patient presented with sudden
onset of amenorrhea, hirsutism and voice changes. Which of the following would
help in diagnosis?
- Testosterone
- 17 hydroxy progesterone
- Dihydroxy epi androsterone
- LH and FSH
Ans 1
120 .The commonest content in vaginal
prolapse is
- Urethrocele
- Cystocele
- Enterocele
- Rectocele
Ans 2
121 .For a menopausal patient having
hot flushes, which of the following can be given as treatment?
- Ethinyl estradiol
- Progesterone
- Gonadotropin
- Danazol
Ans 1
122 .Exfoliative dermatitis is seen
in all the following except
- Pityriasis Rosea
- Pityriasis Rubra pilaris
- Psoriasis
- Drug reaction
Ans
1
123 .In a patient, annular erythematous
lesions on the trunk were seen circumscribed by collarete scales. The diagnosis
is most likely to be
- Pityriasis versicolor
- Pityriasis Rosea
- Pityriasis rubra pilaris
- Lichen planus
Ans
2
124 .Wikham’s striae are seen in
- Lichen sclerosis
- Lichen planus
- Lichen atrophicus
- Psoriasis
Ans 2
125 .A patient with psoriasis was started
on systemic steroids. After stopping treatment, the patient developed generalized
pustules all over his body. The cause is most likely to be
- Drug induced reaction
- Pustular psoriasis
- Bacterial infections
- Septicemia
Ans 2
126 .To do myringotomy, the incision
is put in the posterior inferior region. This is the preferred region for all
the following reasons except
- It is easily accessible
- Damage to chorda tympani
is avoided
- Damage to ossicular chain
does not occur
- It is the least vascular
region.
Ans 4
127 .A false positive fistula test
is seen in all the following except
- Hypermobile ossicular chain
- Labyrinthine fistula
- Dead ear
- Post fenestration
Ans
3
128 .Weber test is done by
- Placing the tuning fork
on the vertex and examined after partial occlusion of the auditory canal
- Placing the tuning fork
on the mastoid and assessing the side of better hearing
- Placing the tuning fork
on the mastoid and examined after partial occlusion of the auditory canal
- Placing the tuning fork
on the forehead and by assessing the side of better hearing
Ans
4
129 .An eight month old infant had
stridor with respiratory difficulty which worsened on crying. On examination,
it was found to have a subglottic reddish mass. All the following can be used
in the management except
- Tracheostomy
- Laser vaporization
- Corticosteroid
- Radiotherapy
Ans
4
130 .A chronic smoker with history
of hoarseness was found on examination to have keratosis of the larynx. All
the following are possible treatment modalities except
- Laser
- Radiotherapy
- Stripping of the vocal cord
- Partial laryngectomy
Ans
4
131 .The treatment of choice of a
glottic cancer with stage T1N0M0 is
- Brachytherapy
- External beam radiotherapy
- Laryngectomy
- Chemotherapy
Ans
2
132 .A 2 year old child develops
acute respiratory distress and was brought to the casualty. On examination,
there were decreased breath sounds with wheeze on the right side. The Chest
Xray showed diffuse opacity in the right hemithorax. Which of the following
is the most likely diagnosis?
- Pneumothorax
- Foreign body aspiration
- Pleural effusion
- Unilateral emphysema
Ans
2
133 .A young boy, ram lal developed
respiratory distress. On examination, the Chest Xray showed hyperinflation of
one lung. Which of the following is the most possible diagnosis?
- Congenital lobar emphysema
- Foreign body aspiration
- Bronchiectasis
- Atelectasis
Ans
2
134 .A 2 year old boy presented with
fever. On examination, he had a respiratory rate of 50 per minute with bilateral
crepitations and no chest indrawing. Cyanosis was present. Which of the following
is the most likely diagnosis?
- Pneumonia
- No pneumonia
- Severe pneumonia
- Upper respiratory tract
infection
Ans
1
135 .Epiphora is
- An epiphenomenon of ophthalmic
allergy
- Excess flow of tears due
to blockade of nasolacrimal duct
- Ectropion is the most common
cause
- Due to irritation of cornea
by eyelashes
Ans
2
136 .You have been referred a case
of open angle glaucoma. Which of the following would be important point in diagnosing
the case?
- Shallow anterior chamber
- Optic disc cupping
- Narrow angle
- Visual acuity and refractive
error
Ans
2
137 .Tonography is important in
- Detecting the formation
of aqueous humor
- Detecting the drainage of
aqueous humor
- Gives continuous intraocular
pressure tracings
- Represents field changes
Ans
2
138 .Cone is the most sensitive cell
in the retina. It picks up images from a mix of red, blue and yellow colors.
Abnormality in color perception needing increased use of red color for normal
perception is
- Protanomaly
- Deuteranomaly
- Tritanomaly
Ans
1
139 .Which color would be best for
foveal color testing?
- Red and Green
- Blue and Green
- Yellow and Green
- Red and Blue
Ans
1
140 .Omar has hypermetropia
needs + 1.5 D glasses for distant vision. What would happen to his near vision
when his glasses slip down his nose?
- Distorted
- Remains unchanged
- Becomes better
- Becomes worse
Ans
1
141 .A 12 year old child with complaints
of headache and decreased vision has visual acuity of 6/36 in the right eye
and 6/6 in the left eye. On Retinoscopy at 66 cms, the right eye showed correction
of 1.5 D and left eye 5 D. The anterior chamber and fundus of the eye were normal.
What may be the cause of decreased vision in the right eye?
- Amblyopia
- Anisometropia
- Optic neuritis
- Refractive error
Ans
1
142 .Oculomotor nerve paralysis causes
all the following except
- Medial rectus
- Lateral rectus
- Inferior oblique
- Levator palpebrae superioris
Ans 2
143 .A patient with photophobia and
redness of the eye, on examination, showed vertically oval and mid dilated pupil.
The diagnosis is
- Acute congestive glaucoma
- Iridocyclitis
- Keratitis
- Conjunctivitis
Ans 1
144 .In a patient with Wernicke’s
presents with hemianopic pupillary response, the most likely site of involvement
is
- Optic nerve
- Optic tract
- Lateral geniculate body
- Optic radiation
Ans 2
145 .You are asked to examine the
peripheral field of vision of a patient. On examination you normally find
decreased field of vision
- Upwards
- Downwards
- Looking towards right side(temporal)
- Looking towards left side
(Nasal)
Ans 1
146 .Which of the following is seen
in Pindborg’s tumor?
- Sunray appearance
- Onion peel appearance
- Driven snow appearance
- Cherry Blossom appearance
Ans
3
147 .All the following are true about
loculated pleural effusion except
- It makes an obtuse angle
with the chest wall
- The margins are diffuse
when viewed end on
- Not confined to any bronchopulmonary
segment
- Air bronchograms are seen
within the opacity
Ans
1
148 .The maximum penetration among
the following is seen with which ray
- Alpha
- Beta
- Gamma
- Electron beam
Ans 3
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149 .In a patient having heavy dense bones, penetration is best achieved by
- Increase in mA
- Increase in kVp
- Increased exposure time
- Increased developing time
Ans 2
150 .Measurement of intravascular
pressure by a pulmonary catheter should be done
- At end expiration
- At peak of inspiration
- During mid expiration
- During mid inspiration
Ans 2
151 .The cumulative pregnancy rate
for Levonorgestrel Intrauterine Device (LN-IUD) for a period of 5 years is
- 0.5
- 1.0
- 1.5
- 2.0
Ans
152 .About direct standardization
all are true except
- Age specific death rate
is not needed
- A standard population is
needed
- Population should be comparable
- Two populations are compared
Ans
1
153 .Active and passive immunity
should be given together in all except
- Tetanus
- Rabies
- Measles
- Hepatitis B
Ans 3
154 .Which of the following statements
is true regarding pertussis?
- Neurological complication
rate of DPT is 1 in 50000
- Vaccine efficacy is more
than 95%
- Erythromycin prevents spread
of disease between children
- Leukocytosis correlates
with the severity of cough
Ans 3
155 .Xavier and Yogender stay in
the same hostel of the same university. Xavier develops infection with Group
B meningococcus. After a few days, Yogender develops infection due to Group
C meningococcus. All the following are true statements except
- Educate students about meningococcal
transmission and take preventive measures
- Chemoprophylaxis against
both Group B and Group C
- Vaccine prophylaxis of contacts
of Xavier
- Vaccine prophylaxis of contacts
of Yogender
Ans 3
156 .Acute flaccid paralysis is reported
in a child aged
- 0-3 years
- 0-5 years
- 0-15 years
- 0-25 years
Ans 3
157 .The infectivity of chicken pox
lasts for
- Till the last scab falls
off
- 6 days after onset of rash
- 3 days after onset of rash
- Till the fever subsides
Ans 2
158 .All the following are sexually
transmitted infections except
- Candida
- Group B streptococcus
- Hepatitis B
- Echinococcus
Ans 4
159 .Which vaccine is contraindicated
in pregnancy?
- Rubella
- Diphtheria
- Tetanus
- Hepatitis B
Ans 1
160 .Positive Schick test indicates
- Immunity to diphtheria
- Susceptibility to diphtheria
- Hypersensitivity to diphtheria
- Infection with diphtheria
Ans 2
161 .Carriers are important in all
the following except
- Polio
- Typhoid
- Measles
- Diphtheria
Ans 3
162 .The most important function
of sentinel surveillance is
- To find total amount of
disease in a population
- To plan effective control
measures
- To determine the trend of
disease in a population
Ans 1
163 .Iron and Folic acid supplementation
forms
- Health promotion
- Specific protection
- Primordial prevention
- Primary prevention
Ans 2
164 .Serial interval is
- Time gap between primary
and secondary case
- Time gap between index and
primary case
- Time taken for a person
from infection to develop maximum infectivity
- The time taken from infection
till a person infects another person
Ans 1
165 .All the following are advantages
of case control studies except
- Useful in rare diseases
- Relative risk can be calculated
- Odds ratio can be calculated
- Cost-effective and inexpensive
Ans 2
166 .For a 60 kg Indian male, the
minimum daily protein requirement has been calculated to be 40 g (mean) ±
10 (Standard deviation). The recommended daily allowance of protein would be
- 60 g/ day
- 70 g/ day
- 40 g/ day
- 50 g/ day
Ans 1
167 .Cereals and proteins are considered
complementary since
- Cereals are deficient in
methionine
- Cereals are deficient in
methionine and pulses are deficient in lysine
- Cereals are deficient in
lysine and pulses are deficient in methionine
- Both cereals and pulses
contain threonine
Ans 3
168 .The biological oxygen demand
indicates
- Organic matter
- Bacterial content
- Anaerobic bacteria
- Chemicals
Ans 1
169 .A population study showed a
mean glucose of 86 mg/ dL. In a sample of 100 showing normal curve distribution,
what percentage of people have glucose above 86%?
- 65
- 50
- 75
- 60
Ans 2
170 .In a study, variation in cholesterol
was seen before and after giving a drug. The test which would give its significance
is
- Unpaired t test
- Paired t test
- Chi square test
- Fisher’s test
Ans 2
171 .The correlation between variables
A and B in a study was found to be 1.1. This indicates
- Very strong correlation
- Moderately strong correlation
- Weak correlation
- Computational mistake in
calculating correlation
Ans 4
172 .The association between coronary
artery disease and smoking was found to be as follows.
|
|
Coronary Art Dis
|
No Coronary Art Dis
|
Smokers
|
30
|
20
|
|
Nonsmokers
|
20
|
30
|
The Odds
ratio can be estimated as
1.
0.65
2.
0.8
3.
1.3
4.
2.25
Ans
4
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173 .In a prospective study comprising
10000 subjects, 6000 subjects were put on beta carotene and 4000 were not. 3
out of the first 6000 developed lung cancer and 2 out of the second 4000 developed
lung cancer. What is the interpretation of the above?
- Beta carotene is protective
in lung cancer
- Beta carotene is not protective
in lung cancer
- The study design is not
sufficient to draw any meaningful conclusions
- Beta carotene is carcinogenic
Ans 2
174 .The best method to show the
association between height and weight of children in a class is by
- Bar chart
- Line diagram
- Scatter diagram
- Histogram
Ans 4
175 .In a low prevalence area for
Hepatitis B, a double ELISA test was decided to be performed in place of a single
test which used to be done. This would cause an increase in the
- Specificity and positive
predictive value
- Sensitivity and positive
predictive value
- Sensitivity and negative
predictive value
- Specificity and negative
predictive value
Ans 1
176 .Retroviruses contain
- DNA polymerase
- Reverse transcriptase
- Segmented DNA
- ds DNA
Ans 2
- Ureteric constriction is seen
at all the following positions except
- Ureteropelvic junction
- Ureterovesical junction
- Crossing of iliac artery
- Ischial spine
Ans 4
178 .A patient with complete transaction
of the spinal cord at the C7 level will show all the following except
- Anesthesia below the level
of lesion
- Areflexia
- Hypotension
- Limited respiratory effort
Ans
4
179 .In unexplained hypotension,
which part of the vertebra should be examined?
- Upper cervical
- Lumbar
- Thoracic
- Lower cervical
Ans
3
180 .In dividing cells, spindle is
formed by
- Ubiquitin
- Tubulin
- Laminin
- Keratin
Ans
2
181 .The superficial external pudendal
artery is a branch of
- Femoral artery
- External iliac artery
- Internal iliac artery
- Aorta
Ans 1
182 .The weight of the upper limb
is transmitted to the axial skeleton by
- Coracoclavicular ligament
- Coracoacromial ligament
- Costoclavicular ligament
- Coracohumeral ligament
Ans
1
183 .Which of the following
muscles is supplied by mandibular nerve
- Masseter
- Buccinator
- Tensor veli palati
- Posterior belly of digastric
Ans
3
184 .Elastic cartilage is found in
- Auditory tube
- Nasal septum
- Articular cartilage
- Costal cartilage
Ans
1
185 .The sensory supply of the palate
is through all the following except
- Facial nerve
- Hypoglossal nerve
- Glossopharyngeal nerve
- Maxillary division of trigeminal
Ans
2
186 .Diaphragmatic hernia can occur
through all the following except
- Esophageal opening
- Costovertebral triangle
- Costal and sternal attachment
of diaphragm
- Inferior vena caval opening
Ans
1
187 .All the following are true regarding
blood supply to the kidney except
- Arcuate artery is an end
artery
- It is a site for portal
systemic anastomosis
- The renal artery divides
into five segmental arteries before entering the hilum
Ans 2
188 .All the following are derivatives
of the neural crest except
- Melanocyte
- Adrenal medulla
- Sympathetic ganglia
- Cauda equina
Ans 4
189 .Which of the following is true
regarding gastrulation?
- Leads to formation of the
three germ layers
- Occurs at the caudal end
prior to the cranial end
- Inner cell mass gives rise
to the yolk sac
- Usually occurs at 4 weeks
Ans 1
190 .All the following are true about
dorsal root ganglia except
- Occurs in the cranial nerves
- Derivative of neural crest
- Contains multipolar cells
- Contains lipofuscin granules
Ans 3
191 .Which of the following is required
for the synthesis of nitric oxide?
- NADPH, NAD, FMN
- Dioxygenase
- NADH
- NADH, FAD
Ans 4
192 .Which of the following is true
regarding hydroxyl ethyl starch?
- It is an anesthetic agent
- It is a plasma expander
- It is a crystalloid
- Used as a nutritional agent
Ans 2
193 .In a well fed state, acetyl
CoA obtained form diet is least used in the synthesis of
- Palmityl CoA
- Citrate
- Acetoacetate
- Oxalosuccinate
Ans 3
194 .Substrate level phosphorylation
is seen in conversion of
- Acetoacetate to alpha keto
glutarate
- Succinyl CoA to Succinate
- Fumarate to malate
- Succinate to fumarate
Ans 2
195 .Elasticity of the corneal layer
of skin is due to the presence of
- Histidine
- Keratin
- Lysine
- Cysteine
Ans 4
196 .Apo B 48 and apo B 100 differ
due to
- RNA splicing
- Apo B gene
- Chromosomal loci
- Gene rearrangement
Ans 1
197 . "All enzymes are not proteins." This statement is justified by
- All enzymes do not follow
the Michaelis Menten hypothesis
- RNA acts as ribozymes
- Antibodies take a part in
the catalysis of many reactions
- Metals are involved in attachment
and catalysis
Ans 2
198 .Enzymes mediating transfer of
one molecule to another are
- Transferases
- Oxidases
- Lyases
- Peptidases
Ans
1
199 .In oxidative phosphorylation,
the ATP production and respiratory chain are linked by
- Chemical methods
- Physical methods
- Chemiosmotic methods
- Conformational changes
Ans 3
200 .In which of the following reactions
is Magnesium required?
- Na-K ATPase
- Transferases
- Phosphatases
- Aldolases
Ans 1
201 .Thiamine level is best monitored
by
- Transketolase level in blood